Objectives/Goals: Differences in gait patterns related to post-traumatic (PTOA) and idiopathic (IDIO) knee osteoarthritis (OA) in aging adults is not well understood. Therefore, the purpose of this study was to assess the impact of knee OA phenotype (PTOA vs IDIO) on the knee total joint moment (TJM) during walking in aging adults with and without end-stage knee OA. Methods/Study Population: Six adults with PTOA and six adults with IDIO were tested prior to knee replacement. Data from 12 healthy, asymptomatic adults were used as control data. All subjects underwent 3D gait analysis at a self-selected speed. TJM was calculated as the square root of the sum of the squared planar internal sagittal, frontal, and transverse plane knee moments across the stance phase. The corresponding sagittal, frontal, and transverse plane moments at the peak TJM in the 1st (TJM1) and 2nd (TJM2) half of the stance phase were extracted. A repeated-measures ANOVA was used to assess group differences in biomechanical parameters of the dominant (control group) and surgical (OA groups) limb, while knee pain (VAS: 0 – 10) during the walking task for the PTOA and IDIO groups was compared using an independent t-test (alpha=0.05). Results/Anticipated Results: Both the PTOA and IDIO groups walked at slower speeds compared to the control group (p 0.05). In addition, there were no differences in self-reported knee pain during walking between the PTOA and IDIO groups (p=0.25). Discussion/Significance of Impact: People with PTOA exhibit more rapid knee joint degeneration than those with IDIO. Lower frontal plane loading during TJM2 in PTOA may be associated with a more rapid decline in knee muscle function. Further evaluation of knee muscle function in PTOA and IDIO will provide better insight into these differences in gait patterns between PTOA and IDIO.
Jacobs et al. (2026) studied this question.