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May 9, 2026Angiology3 citations

Inflammatory Prognostic Index May Predict the Development of Contrast-Induced Nephropathy in Patients with ST-Segment Elevation Myocardial Infarction

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YCYusuf CanEEEmre EynelŞÖŞevval Özdemir

Key Points

  • This research aims to evaluate the effectiveness of the inflammatory prognostic index (IPI) in predicting contrast-induced nephropathy (CIN) in ST-segment elevation myocardial infarction (STEMI) patients.
  • Conducted a receiver operating characteristic analysis to compare IPI with other prognostic markers.
  • Analyzed data related to admission parameters including age, blood urea nitrogen, and ejection fraction.
  • Determined an IPI cutoff value for predicting CIN with sensitivity and specificity metrics.
  • IPI showed superior discriminative performance (AUC 0.826, 95% CI 0.783-0.869) in predicting CIN compared to NLR (AUC 0.691), CAR (AUC 0.712), and SII (AUC 0.704).
  • An IPI cutoff of 8.35 predicted CIN with 82.4% sensitivity and 65.9% specificity.

Abstract

= .013), together with advanced age, higher blood urea nitrogen levels, reduced left ventricular ejection fraction, history of stroke, and the occurrence of no-reflow. Receiver operating characteristic analysis demonstrated superior discriminative performance for IPI (area under the curve AUC 0.826, 95% CI 0.783-0.869) compared with neutrophil-to-lymphocyte ratio (NLR; AUC 0.691), C-reactive protein-to-albumin ratio (CAR; AUC 0.712), and systemic immune inflammation index (SII; AUC 0.704). An admission IPI cutoff value of 8.35 predicted CIN with 82.4% sensitivity and 65.9% specificity. IPI demonstrates superior discriminative performance compared with CAR, NLR, and SII for predicting CIN in STEMI patients undergoing pPCI.

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Cite This Study

Can et al. (2026) studied this question.

synapsesocial.com/papers/69fed008b9154b0b82876fb1https://doi.org/10.1177/00033197261447011
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