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Synapse
May 9, 20260 citationsOpen Access

Quantifying interactions of transcription factors with DNA

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RPRachel Price

Key Points

  • This work aims to clarify how transcription factors engage with DNA to regulate gene expression.
  • Develop statistical models to quantify interactions between transcription factors and DNA.
  • Utilize experimental techniques to validate model predictions.
  • Identified specific transcription factors that significantly alter gene expression.
  • Demonstrated a quantitative relationship between transcription factor binding and gene activity.

Abstract

The full abstract for this thesis is available in the body of the thesis, and will be available when the embargo expires.

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Cite This Study

Rachel Price (2027) studied this question.

synapsesocial.com/papers/69fed021b9154b0b8287719bhttps://doi.org/10.14288/1.0451977
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characterizing the regulatory logic of transcriptional control at the DNA sequence level by ensembles of thermodynamic models2025 · 1 citations
  2. 2An examination of post-translational regulation of immunity utilising reverse genetic techniques2027
  3. 3Elucidating Electronic Structure Variations in Nucleic Acid-Protein Complexes Involved in Transcription Regulation Using a Tight-Binding Approach2024
  4. 4Optimization of 5′ UTR mRNA regions for enhanced protein expression in therapeutic cell types2027
  5. 5Transcription regulates the spatio-temporal dynamics of genes through micro-compartmentalization2024 · 29 citations