Objectives/Goals: Building on Schneider et al., which mapped translational science (TS) principles across urban CTSA hubs, evaluators and one pilots administrator within the Consortium of Rural States CTSAs examined how hubs prioritize these principles. This work can ensure shared TS values and inform a common rubric across rural CTSA institutions. Methods/Study Population: We analyzed CORES ranking data from eight CTSA hubs ( n = 49 respondents). Item-level mean ranks and standard deviations summarized TS principle priorities, while respondent-averaged means reduced bias from unequal item counts. Site-level profiles were compared using Spearman rank correlations to examine cross-hub similarity. Results/Anticipated Results: Our analysis of CORES data (8 hubs, n = 49) replicates Schneider et al.’s finding that TS solutions center on generalizable solutions and efficiency/speed. Rural hub rankings showed tight agreement and low dispersion, confirming these as shared core TS values. Despite differing experimental and hub contexts, the pattern mirrors Schneider et al. (2024) and strengthens support that NCATS’ TS principles apply consistently across both urban and rural CTSA hubs. Discussion/Significance of Impact: CORES hubs prioritized Translational Science (TS) projects emphasizing generalizable solutions and efficiency, reflecting shared values. Findings align with prior TS/TR work and support creating a concise, qualitative TS rubric to guide co-funded projects with system-level impact.
Eggleston et al. (2026) studied this question.