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April 20, 2018Science760 citationsOpen Access

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

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MFMariella G. FilbinITItay TiroshVHVolker Hovestadt

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Abstract

signaling. Our study characterizes oncogenic and developmental programs in H3K27M-glioma at single-cell resolution and across genetic subclones, suggesting potential therapeutic targets in this disease.

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Filbin et al. (2018) studied this question.

synapsesocial.com/papers/69ff5e8d6018b8d0892d7b76https://doi.org/10.1126/science.aao4750
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