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May 10, 2026Annals of Surgical Treatment and Research1 citationsOpen Access

Clinical efficacy of parathyroid autotransplantation into the forearm muscle in thyroid surgery: a retrospective cohort study on functional restoration

LBLifen BaiHZHuiyin ZhuLZLing Zhou

Key Points

  • This research aims to evaluate the effectiveness of autologous parathyroid transplantation during thyroid surgery and the recovery of graft function over time.
  • Retrospective cohort study of 52 patients undergoing thyroid surgery with autologous parathyroid transplantation.
  • Measured serum parathyroid hormone levels at various postoperative intervals.
  • Recorded instances of hypoparathyroidism.
  • Postoperative PTH levels were significantly higher on the transplant side from week 1 to 1 year.
  • Graft effectiveness rates increased from 1.9% (day 1) to 84.6% (1 month), stabilizing around 73% after 1 year.
  • Transient hypoparathyroidism occurred in 17.3% of patients, with no cases of permanent hypoparathyroidism.

Abstract

Purpose: This study was conducted to evaluate the clinical efficacy of autologous parathyroid transplantation into the forearm brachioradialis muscle during thyroid surgery and analyze the timing of graft function recovery.Methods: A total of 52 patients undergoing thyroid surgery with autologous parathyroid transplantation were selected.Serum parathyroid hormone (PTH) levels were measured at various postoperative intervals, and instances of hypoparathyroidism were recorded.Results: Postoperative PTH levels on the transplant side were significantly higher than on the non-transplant side from week 1 to 1 year.Effective graft rates were 1.9% on day 1, 40.4% at week 1, 84.6% at 1 month, and stabilized at around 73% after 1 year.Transient hypoparathyroidism was observed in 17.3% of patients, with no permanent cases.Conclusion: Autologous parathyroid transplantation into the forearm brachioradialis muscle effectively preserves parathyroid function, with grafts regaining optimal function within 2-3 months and the graft still having good secretory function 1 year after surgery.

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Cite This Study

Bai et al. (2026) studied this question.

synapsesocial.com/papers/6a00205ec8f74e3340f9b38chttps://doi.org/10.4174/astr.2026.110.5.311
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