Background: Aesthetic surgery tourism has seen a significant increase in recent years. However, patients undergoing long-haul flights after surgery may be at higher risk for complications due to physiological changes associated with air travel. This study examines the impact of commercial flight conditions on postoperative patients traveling after aesthetic procedures. Methods: This prospective study evaluated physiological variables in postoperative patients undergoing aesthetic surgery tourism during flights exceeding 4 hours. Oxygen saturation, heart rate, and popliteal vein diameter were monitored throughout the flight. The findings were compared with a control group of nonsurgical travelers. The study also analyzed the potential contribution of these physiological changes to postoperative complications. Results: All postoperative patients experienced oxygen desaturation, with an average drop of 4%–7% in hemoglobin saturation within the first 4 hours of flight. Postoperative patients also exhibited significantly lower baseline hemoglobin levels compared with presurgical levels. Heart rate increased by 15–20 bpm in all participants, and popliteal vein diameter progressively expanded throughout the flight due to hypoxia-induced vasodilation and prolonged sitting. These physiological alterations align with risk factors for thrombosis, flap necrosis, infection, and postoperative bleeding. Conclusions: Patients undergoing aesthetic surgery tourism experience decreased oxygen saturation, increased heart rate, and an enlarged popliteal vein diameter due to the body’s intrinsic responses to hypoxia. These physiological changes, combined with their postoperative state, may increase the risk of complications such as thrombosis, necrosis, infection, hematomas, and bleeding. Postoperative care protocols and preflight counseling are essential to ensure patient safety and mitigate these risks.
Ramírez et al. (2026) studied this question.