0744 A Systematic Review of Non-Pharmacological Interventions for Central Disorders of Hypersomnolence: Highlighting Lived Experience Involvement

Abstract Introduction People with central disorders of hypersomnolence (CDH), which include Narcolepsy Types 1 n=3), mindfulness-based (MBI; n=1), and meditation-relaxation therapy (MR therapy; n=1) interventions. Extended nocturnal sleep interventions for narcolepsy generally reported improvements in daytime sleepiness. Napping intervention results for narcolepsy were inconsistent. Psychology interventions (CBT, MBI, and MR therapy) found generally positive results on their primary outcomes; CBT and MBI interventions significantly improved some mental health outcomes; CBT for Nightmares significantly improved nightmare severity; and MR therapy significantly improved sleep paralysis. All studies were pilot or feasibility studies with small sample sizes and good acceptability. One psychology intervention and no napping or sleep schedule interventions were tested with people with IH. People with narcolepsy were involved in three studies, but reporting was limited and did not use recommended reporting procedures. No people with IH were involved in the design of any interventions. Conclusion There has been recent progress in developing adjunctive non-pharmacological interventions for people with CDH that show promising effectiveness. However, involvement of people with CDH using standardised reporting, especially with people with IH, is absent and should be incorporated into future research. Support (if any) Sleep Disorders Australia; ARC Life Course Centre; Australian Government.