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May 11, 2026Cureus0 citationsOpen Access

A Review of Hand Neuroanatomy, Anesthesia, and Bedside Blockade

APAneri U. PatelAGAlisa O. GirardAFAlec H. Fisher

Key Points

  • This review aims to provide a comprehensive reference for administering regional anesthesia in the hand and wrist at bedside procedures.
  • Literature review on anesthetic agents and neuroanatomy of the hand.
  • Discussion among a board-certified hand surgeon and plastic surgery residents about practical skills.
  • Evaluation of techniques for effective bedside nerve blocks, including ultrasound guidance.
  • Awake children receiving bedside nerve blocks achieved high efficacy and low complication rates.
  • Nerve blockade avoids multiple painful injection sites, reducing patient discomfort.
  • Knowledge of neuroanatomy and dosing minimizes risks of local anesthetic systemic toxicity.

Abstract

Many hand-related pathologies can be appropriately managed at the bedside without operative escalation, thereby reducing resource allocation, healthcare costs, and exposure to general anesthesia. Plastic surgery trainees have variable experience and knowledge in managing hand pathologies outside the operating room. A comprehensive clinical reference for hand anesthesia has yet to be seen in the current plastic surgery literature. This review aims to guide the safe and effective administration of regional anesthesia in the hand and wrist for bedside procedures. This review was guided by clinical experience at a high-volume Level I trauma center in the Northeastern United States. A board-certified hand surgeon and plastic surgery residents discussed practical skills and concepts commonly applied to hand procedures performed in the emergency department. A review of the literature was performed, investigating anesthetic agents, considerations for use, neuroanatomy of the hand, and versatile blockade techniques. In contrast to local infiltration, nerve blockade reaches deeply innervated structures while avoiding multiple painful injection sites, tissue distortion, and wound contamination. Nerve blocks are discouraged in patients who are unable to communicate symptoms of intraneural injection. However, bedside nerve blocks in awake children achieve high efficacy and low complication rates, particularly when ultrasound-guided injection or sedation is employed. Local anesthetic systemic toxicity can be avoided through knowledge of anatomical landmarks, anesthetic characteristics, and appropriate dosing. The hand has complicated yet predictable neurovascular anatomy. With proper anesthetic administration, a remarkable degree of patient comfort and a high level of procedural complexity can be achieved outside the operating room.

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Cite This Study

Patel et al. (2026) studied this question.

synapsesocial.com/papers/6a0171ce3a9f334c28271d3bhttps://doi.org/10.7759/cureus.108516
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