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October 12, 2022Frontiers in Cellular and Infection Microbiology21 citationsOpen Access

A multiplex pneumonia panel for diagnosis of hospital-acquired and ventilator-associated pneumonia in the era of emerging antimicrobial resistance

AJAnupop JitmuangSPSoravit PuttinadSHSivaporn Hemvimol

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Abstract

Background: Antimicrobial resistance (AMR), including multidrug (MDR) and extensively drug-resistant (XDR) bacteria, is an essential consideration in the prevention and management of hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP). In the AMR era, the clinical utility of the BioFire FilmArray Pneumonia Panel Plus (BFPP) to diagnose HAP/VAP has not been thoroughly evaluated. Methods: We enrolled adult hospitalized patients with HAP or VAP at Siriraj Hospital and Saraburi Hospital from July 2019-October 2021. Respiratory samples were collected for standard microbiological assays, antimicrobial susceptibility testing (AST), and the BFPP analysis. Results: . Conclusions: and discordance of AMR gene results limit the test performance.

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Jitmuang et al. (2022) studied this question.

synapsesocial.com/papers/6a0230ae8b14fde368dcf299https://doi.org/10.3389/fcimb.2022.977320
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