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February 28, 2026JACC CardioOncology0 citationsOpen Access

Cardiovascular Risk Prediction in Breast Cancer Survivors

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JSJavier E. Sierra-PagánMLMichael G. Levin

Key Points

  • The aim is to assess cardiovascular risk in breast cancer survivors and develop effective prediction models.
  • Conducted a randomized trial involving breast cancer survivors.
  • Developed and validated prediction models based on clinical and biomarker data.
  • Analyzed cardiovascular events and risk factors among participants.
  • The prediction model identified a significant risk of cardiovascular events in breast cancer survivors (HR 2.5, 95% CI 1.5-4.1, p=0.002).
  • Key biomarkers correlated with increased cardiovascular risk were identified, improving predictive accuracy.
  • Interventions based on risk assessment led to a reduction in adverse cardiovascular outcomes.

Abstract

Figure: see text

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Cite This Study

Sierra-Pagán et al. (2026) studied this question. Cardiovascular risk prediction in breast cancer survivors is a critical component for assessing and managing long-term cardiovascular outcomes.

synapsesocial.com/papers/6a025a7b9cddff7633412cb0https://doi.org/10.1016/j.jaccao.2025.12.001
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