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March 31, 2026The Lancet10 citations

Atrial fibrillation

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DLDeirdre A LaneJAJason G AndradeEAElena Arbelo

Key Result

Atrial fibrillation affects approximately 37.6 million people worldwide, with its prevalence predicted to double over the next 35 years, necessitating integrated care and risk factor management.

Key Points

  • To address the rising prevalence of atrial fibrillation and its associated risks and management strategies.
  • Review of diagnostic technologies including wearable devices for detecting atrial fibrillation.
  • Analysis of patient-centered care strategies to manage comorbidities and risk factors.
  • Evaluation of guidelines for integrated care approaches in atrial fibrillation management.
  • Atrial fibrillation prevalence predicted to double to 75.6 million by 2058.
  • Effective stroke prevention through patient empowerment and oral anticoagulation significantly improves health outcomes.
  • Multidisciplinary care approaches enhance identification and management of risk factors associated with atrial fibrillation.

Structured PICO

P
Population
Patients with atrial fibrillation

A comprehensive review highlighting the increasing prevalence of atrial fibrillation, the role of new detection technologies, and the importance of integrated, patient-centered care including anticoagulation and risk factor management.

Abstract

Atrial fibrillation affects approximately 37·6 million people worldwide, with the prevalence predicted to double over the next 35 years. The ubiquitous use of wearable devices and other technologies with inbuilt diagnostic algorithms allows greater detection of atrial fibrillation among the general public than previously. Atrial fibrillation increases the risk of stroke and thromboembolism, heart failure, and death, and is associated with reductions in quality of life. Patients with atrial fibrillation frequently have comorbidities, and the accumulation of risk factors, including lifestyle factors associated with poorer health outcomes, and increasing age, often adds to the complexity of managing such patients. All major clinical guidelines advocate that stroke prevention, symptom relief, identification of risk factors, and optimisation of risk factor management, incorporated into an integrated care approach, with multidisciplinary input as required, are essential elements of atrial fibrillation management. Avoidance of stroke with oral anticoagulation remains the default for most patients with atrial fibrillation and, more recently, catheter ablation has been reconsidered as an initial treatment option for symptom relief. The dynamic nature of risk factors requires early identification and appropriate management of new and existing risk factors to optimise atrial fibrillation care. Patient-centred care and better health literacy can empower patients to take a more active role in their atrial fibrillation management.

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Cite This Study

Lane et al. (2026) conducted a review in Atrial fibrillation. Atrial fibrillation affects approximately 37.6 million people worldwide, with its prevalence predicted to double over the next 35 years, necessitating integrated care and risk factor management.

synapsesocial.com/papers/6a025ca6edf6f48138594843https://doi.org/10.1016/s0140-6736(25)02166-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparing Bleeding Risk Assessment Focused on Modifiable Risk Factors Only Versus Validated Bleeding Risk Scores in Atrial Fibrillation2017 · 70 citations
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  3. 3Atrial Fibrillation and Stress2022 · 39 citations
  4. 4Clinical Impact of Early Rhythm Control and Healthy Lifestyles in Patients With Atrial Fibrillation2024 · 12 citations
  5. 5Early Rhythm Control and the Risks of Ischemic Stroke, Heart Failure, Mortality, and Adverse Events When Performed Early (<3 Months): A Nationwide Cohort Study of Newly Diagnosed Patients with Atrial Fibrillation2022 · 43 citations