Does long-term cumulative blood pressure predict the risk of cardiovascular outcomes better than single measurements in middle-aged and older adults without baseline CVD?
Cumulative blood pressure over time provides a better prediction of cardiovascular outcomes than a single blood pressure measurement in middle-aged and older adults.
BACKGROUND: Cardiovascular disease (CVD) remains a major health concern globally, contributing to a considerable disease burden. However, few studies have considered long-term cumulative blood pressure (cBP) exposure in middle-aged and older population in China. The aim of this study was to investigate whether long-term cBP was associated with subsequent cardiovascular outcomes among participants without CVD at baseline in Chinese over 45 years old. METHODS: 6435 participants in China of the CHARLS (The China Health and Retirement Longitudinal Study) were included. Cumulative BP was calculated as the area under the curve using measurements from wave 1 (2011) to wave 2 (2013). Outcomes included CVD, heart disease and stroke. RESULTS: < .001). CONCLUSIONS: Long-term cSBP, cDBP and cMAP were associated with subsequent CVD and only found in people younger than 60 years of age, whereas cPP was associated with stroke only across all ages. Cumulative BP may provide a better prediction of cardiovascular outcomes compared with single BP measurement. Efforts are required to control long-term BP in assessing cardiovascular risks.
You et al. (2025) studied this question.