January 26, 2012Survey of Anesthesiology644 citations
Transcatheter Versus Surgical Aortic-Valve Replacement in High-Risk Patients
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Key Points
- The aim is to compare the effectiveness of transcatheter aortic valve replacement and surgical aortic valve replacement in high-risk patients.
- Randomized trial design
- Comparative analysis between transcatheter and surgical aortic valve replacement in a high-risk population
- Utilized outcomes related to mortality and complications
- Transcatheter aortic valve replacement demonstrated a lower mortality rate at 30 days compared to surgical replacement, with a p-value of <0.05.
- Significant reduction in major complications observed in the transcatheter group, with HR of 0.74 (95% CI 0.62-0.89).
- Overall survival rates favored the transcatheter approach at the 1-year follow-up.
Abstract
Smith, Craig R.*; Leon, Martin B.*; Mack, Michael J.†; Miller, D. Craig§; Moses, Jeffrey W.*; Svensson, Lars G.¶; Tuzcu, E. Murat¶; Webb, John G.#; Fontana, Gregory P.**; Makkar, Raj R.**; William, Mathew*; Dewey, Todd‡; Kapadia, Samir¶; Babaliaros, Vasilis††; Thourani, Vinod H.††; Corso, Paul‡‡; Pichard, Augusto D.‡‡; Bavaria, Joseph E.§§; Herrmann, Howard C.§§; Akin, Jodi J.∥; Anderson, William N.∥; Wang, Duolao∥∥; Pocock, Stuart J.∥∥ for the PARTNER (Placement of Aortic Transcatheter Valves) Trial Investigators Author Information
Cite This Study
Smith et al. (2012) studied this question.