A large-scale HFMD outbreak in France involving 3,403 cases was predominantly associated with Coxsackievirus A6, which was detected in 49.5% of enterovirus-positive clinical samples.
Observational (n=3,403)
A large-scale outbreak of atypical HFMD in France was predominantly driven by Coxsackievirus A6, highlighting the need for ongoing syndromic and virological surveillance.
We report a large-scale outbreak of hand, foot and mouth disease (HFMD) in France. As at 28 September 2021, 3,403 cases have been reported (47% higher than in 2018-19). We prospectively analysed 210 clinical samples; 190 (90.5%) were enterovirus-positive. Most children presented with atypical HFMD. Coxsackievirus (CV)A6 (49.5%; 94/190) was predominant; no enterovirus A71 was detected. Dermatological and neurological complications of HFMD justify prospective syndromic and virological surveillance for early detection of HFMD outbreaks and identification of associated types.
Mirand et al. (2021) conducted an observational in Hand, foot and mouth disease (HFMD) (n=3,403). A large-scale HFMD outbreak in France involving 3,403 cases was predominantly associated with Coxsackievirus A6, which was detected in 49.5% of enterovirus-positive clinical samples.