Key points are not available for this paper at this time.
Split personality: A series of oligoamide-based helix mimetics bind to a complementary helical motif in Islet amyloid polypeptide (IAPP), a protein implicated in the pathology of type II diabetes. These compounds accelerated IAPP amyloid formation under lipid-free conditions, but inhibited it under lipid-catalyzed conditions. hIAPP=human IAPP.
Saraogi et al. (2009) studied this question.