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August 25, 2007Angewandte Chemie International Edition135 citations

A Palladium‐Catalyzed Regiospecific Synthesis of N‐Aryl Benzimidazoles

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NZNan ZhengKAKevin W. AndersonXHXiaohua Huang

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Abstract

Highly tolerated: A catalytic method employing Pd2 (dba) 3 and XPhos or RuPhos permits the efficient synthesis of N-aryl benzimidazoles in regioisomerically pure form starting from ortho-haloanilides (see scheme), and tolerates a wide range of functional groups. dba=trans, trans-dibenzylideneacetone. Supporting information for this article is available on the WWW under http: //www. wiley-vch. de/contents/jc₂002/2007/z702542ₛ. pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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Cite This Study

Zheng et al. (2007) studied this question.

synapsesocial.com/papers/6a05588a433f4535d70af97bhttps://doi.org/10.1002/anie.200702542
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