Short-term systolic blood pressure variability was associated with an increased risk of dialysis initiation or transplantation in patients with CKD (HR 1.47; 95% CI 1.09-1.99).
Cohort
Does short-term systolic blood pressure variability increase the risk of kidney disease progression in patients with chronic kidney disease?
Short-term systolic blood pressure variability is independently associated with an increased risk of dialysis initiation or transplantation in patients with chronic kidney disease.
Effect estimate: HR 1.47 (95% CI 1.09-1.99)
p-value: p=0.005
=0.005). w-SD of SBP was associated with an increased risk of renal outcomes, both as a continuous variable (hazard ratio HR, 1.47; 95% CI, 1.09-1.99) and as a categorical variable (quartile 4 versus quartile 1: HR, 1.60; 95% CI, 1.08-2.36), independent of 24-hour SBP, daytime SBP, and nighttime SBP. Conclusions Short-term SBP was independently associated with the risk of dialysis initiation and/or transplantation in patients with chronic kidney disease.
Wang et al. (2020) conducted a cohort in Chronic Kidney Disease. Short-term systolic blood pressure variability (w-SD of SBP) vs. Lower variability (Quartile 1) was evaluated on Dialysis initiation and/or transplantation (HR 1.47, 95% CI 1.09-1.99, p=0.005). Short-term systolic blood pressure variability was associated with an increased risk of dialysis initiation or transplantation in patients with CKD (HR 1.47; 95% CI 1.09-1.99).