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May 15, 2026Journal of the American College of Cardiology147 citations

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: Executive Summary

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MGMartha GulatiPLPhillip D. LevyDMDebabrata Mukherjee

Key Result

The 2021 clinical practice guideline provides evidence-based recommendations and algorithms for the risk stratification and diagnostic workup of adult patients presenting with chest pain.

Key Points

  • This guideline aims to provide clinicians with recommendations for the evaluation and diagnosis of chest pain in adults.
  • Comprehensive literature search conducted from November 2017 to May 2020
  • Utilized English publications from major medical databases including PubMed and Cochrane
  • Included guidelines that emphasize risk stratification and cost-value considerations in diagnostic testing.
  • The guidelines recommend algorithms for assessing chest pain based on contemporary evidence.
  • Shared decision-making with patients is advocated for, enhancing the diagnostic process.
  • Recommendations integrate cost-value considerations for diagnostic tests.

Structured PICO

P
Population
Adult patients with chest pain
I
Intervention
Clinical practice guideline recommendations and algorithms for the evaluation, risk stratification, and diagnosis of chest pain

This executive summary provides updated, evidence-based clinical practice guidelines for the assessment, risk stratification, and diagnostic workup of adult patients presenting with chest pain.

Abstract

AIM This executive summary of the clinical practice guideline for the evaluation and diagnosis of chest pain provides recommendations and algorithms for clinicians to assess and diagnose chest pain in adult patients. METHODS A comprehensive literature search was conducted from November 11, 2017, to May 1, 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Collaboration, Agency for Healthcare Research and Quality reports, and other relevant databases. Additional relevant studies, published through April 2021, were also considered. STRUCTURE Chest pain is a frequent cause for emergency department visits in the United States. The "2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain" provides recommendations based on contemporary evidence on the assessment and evaluation of chest pain. These guidelines present an evidence-based approach to risk stratification and the diagnostic workup for the evaluation of chest pain. Cost-value considerations in diagnostic testing have been incorporated and shared decision-making with patients is recommended.

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Cite This Study

Gulati et al. (2021) conducted a review in Chest pain. Guideline recommendations for evaluation and diagnosis was evaluated. The 2021 clinical practice guideline provides evidence-based recommendations and algorithms for the risk stratification and diagnostic workup of adult patients presenting with chest pain.

synapsesocial.com/papers/6a0690c0eefd33dea44b6f7ehttps://doi.org/10.1016/j.jacc.2021.07.052
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