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May 15, 2026The Analyst0 citations

Biochemical Composition of Prostate Core-Needle Biopsies Before and After a Single Fraction of 13.5 Gy: A Raman Spectroscopy-Based Study

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KMKirsty MilliganOkanagan CollegeMWMitchell WiebeOkanagan CollegeAFAlejandra FuentesOkanagan College

Key Points

  • To investigate the biochemical composition of prostate core-needle biopsies in response to radiation therapy.
  • Utilized Raman spectroscopy to analyze biopsies
  • Compared biochemical changes before and after treatment
  • Focused on patients with favourable-risk intermediate-grade prostate cancer
  • Identified significant biochemical alterations in biopsies post-treatment
  • Demonstrated a correlation between radiation dose and biochemical response
  • Highlighted potential for Raman spectroscopy in assessing tumor response

Abstract

High dose rate brachytherapy (HDR-BT) is an attractive option for patients with favourable-risk intermediate-grade prostate cancer. However the relationship between radiation dose and the biochemical response of tumours remains poorly...

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Cite This Study

Milligan et al. (2026) studied this question.

synapsesocial.com/papers/6a06b83de7dec685947aacb0https://doi.org/10.1039/d6an00128a
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