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May 15, 2026Current Otorhinolaryngology Reports0 citationsOpen Access

Posterior Nasal Nerve Procedural Outcomes: Does the Presence of Allergy Matter?

EWEsther WangUniversity of Southern CaliforniaTNTinh Duc NguyenUniversity of Southern CaliforniaRSRodney J. SchlosserMedical University of South Carolina

Key Points

  • To evaluate whether the type of rhinitis (allergic vs. non-allergic) affects outcomes after posterior nasal nerve ablation procedures.
  • Evaluated outcomes of PNN ablation procedures including cryoablation, radiofrequency ablation, and neurectomy.
  • Reviewed studies comparing symptom and quality of life improvements in patients with allergic and non-allergic rhinitis.
  • Analyzed two systematic reviews focusing on 12-month outcomes post-procedure.
  • No significant difference in symptom improvement between allergic rhinitis (AR) and non-allergic rhinitis (NAR) patients overall.
  • Individuals with NAR observed greater symptomatic improvement at 12 months than those with AR.
  • Both AR and NAR patients benefited from PNN ablation in symptom control, with NAR potentially showing more long-term benefits.

Abstract

Abstract Purpose of Review To summarize posterior nasal nerve (PNN) ablation procedures and whether the etiology of rhinitis—allergic (AR) vs. non-allergic (NAR)—modifies post-procedural outcomes of symptoms and quality of life improvements. Recent Findings Three main procedures are used to target the PNN in patients with chronic rhinitis: cryoablation, radiofrequency ablation, and posterior nasal nerve neurectomy. Patients with chronic rhinitis have improvement in their symptoms with all three. When these results were analyzed by allergy status, most studies found no significant difference in the magnitude of benefit between the subgroups. Two systematic reviews found that individuals with NAR have greater symptomatic improvement at 12 months than those with AR. Summary Both AR and NAR patients received benefit in symptom control after PNN ablation procedures, with possibly more benefit in NAR patients in the longer-term. Further studies with adequate power and standardized diagnostic criteria are needed to confirm these findings.

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a06b888e7dec685947aaf4fhttps://doi.org/10.1007/s40136-026-00551-1
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