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May 15, 2026Microbiology and Molecular Biology Reviews2 citations

Roles of transcription factors and chromatin remodelers in regulating innate immune responses in Caenorhabditis elegans

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PWPaaramitha S. WarushavithanaDHDustin T HowardJWJordan D. West

Key Points

  • This research aims to explore how transcription factors and chromatin remodelers influence immune responses in C. elegans.
  • Investigated the roles of specific transcription factors and chromatin remodelers.
  • Analyzed transcriptional control mechanisms in response to various pathogens.
  • Identified conserved and novel principles of immune regulation in C. elegans.
  • Demonstrated key interactions between transcription factors and chromatin remodelers that enhance immune responses.

Abstract

continues to uncover both conserved and novel principles of immune regulation, offering insight into how organisms integrate transcriptional control with physiological constraints to thrive in a pathogen-rich environment.

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Cite This Study

Warushavithana et al. (2026) studied this question.

synapsesocial.com/papers/6a06b95be7dec685947abecchttps://doi.org/10.1128/mmbr.00170-25
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