ABSTRACT Herein, we report the imidation of the C(sp 3 )─H adjacent to the nitrogen atom of N ‐benzyl amides, leading to a variety of amido aminal structures, using N ‐bromoimides as the imide source. The reaction does not employ transition metals and is highly selective towards the formation of the amido aminal group. Preliminary studies indicated that the reaction would occur through three consecutive steps: N ‐bromination of the amide, deprotonation, and nucleophilic addition of in situ‐formed imide.
Jean Le Bras (2026) studied this question.