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January 31, 2012Circulation390 citationsOpen Access

Ideal Cardiovascular Health and Mortality From All Causes and Diseases of the Circulatory System Among Adults in the United States

EFEarl S. FordKGKurt J. GreenlundYHYuling Hong

Key Result

Meeting ≥5 ideal cardiovascular health metrics compared with meeting none was associated with a 78% reduction in all-cause mortality (HR 0.22; 95% CI 0.10-0.50).

Key Points

  • This study aims to investigate how ideal cardiovascular health metrics relate to mortality from all causes and circulatory diseases in adults in the U.S.
  • Analyzed data from 7622 adults aged ≥20 from the National Health and Nutrition Examination Survey (1999-2002) with follow-up data until 2006.
  • Assessed the relationship between the number of ideal cardiovascular health metrics and mortality outcomes.
  • Used alternative measures for dietary and glycemic metrics.
  • 532 deaths occurred during the median follow-up of 5.8 years, including 186 from circulatory diseases.
  • Participants meeting ≥5 metrics experienced a 78% reduced risk of all-cause mortality (adjusted hazard ratio 0.22; 95% CI 0.10-0.50).
  • A reduction of 88% in risk for mortality from circulatory system diseases was noted for those meeting ≥5 metrics (adjusted hazard ratio 0.12; 95% CI 0.03-0.57).

Study Design

Type

Cohort (n=7,622)

Multicenter

Yes

Structured PICO

Does meeting a higher number of ideal cardiovascular health metrics reduce mortality from all causes and diseases of the circulatory system in adults?

P
Population
7,622 adults ≥20 years of age from the United States who participated in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2002
I
Intervention
Meeting ≥5 ideal cardiovascular health metrics (out of 7 American Heart Association metrics)
C
Comparator
Meeting none of the 7 ideal cardiovascular health metrics
O
Outcome
Mortality from all causes and diseases of the circulatory systemhard clinical

Meeting a higher number of ideal cardiovascular health metrics is strongly associated with a significantly reduced risk of all-cause and cardiovascular mortality.

Main Result

Effect estimate: HR 0.22 (95% CI 0.10-0.50)

Abstract

BACKGROUND: Recently, the American Heart Association developed a set of 7 ideal health metrics that will be used to measure progress toward their 2020 goals for cardiovascular health. The objective of the present study was to examine how well these metrics predicted mortality from all causes and diseases of the circulatory system in a national sample of adults in the United States. METHODS AND RESULTS: We used data from 7622 adults ≥20 years of age who participated in the National Health and Nutrition Examination Survey from 1999 to 2002 and whose mortality through 2006 was determined via linkage to the National Death Index. For the dietary and glycemic metrics, we used alternative measures. During a median follow-up of 5.8 years, 532 deaths (186 deaths resulting from diseases of the circulatory system) occurred. About 1.5% of participants met none of the 7 ideal cardiovascular health metrics, and 1.1% of participants met all 7 metrics. The number of ideal metrics was significantly and inversely related to mortality from all causes and diseases of the circulatory system. Compared with participants who met none of the ideal metrics, those meeting ≥5 metrics had a reduction of 78% (adjusted hazard ratio, 0.22; 95% confidence interval, 0.10-0.50) in the risk for all-cause mortality and 88% (adjusted hazard ratio, 0.12; 95% confidence interval, 0.03-0.57) in the risk for mortality from diseases of the circulatory system. CONCLUSION: The number of ideal cardiovascular health metrics is a strong predictor of mortality from all causes and diseases of the circulatory system.

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Cite This Study

Ford et al. (2012) conducted a cohort in Cardiovascular health (n=7,622). Meeting ≥5 ideal cardiovascular health metrics vs. Meeting 0 ideal cardiovascular health metrics was evaluated on All-cause mortality (HR 0.22, 95% CI 0.10-0.50). Meeting ≥5 ideal cardiovascular health metrics compared with meeting none was associated with a 78% reduction in all-cause mortality (HR 0.22; 95% CI 0.10-0.50).

synapsesocial.com/papers/6a06f26b02b4a6d6a3d3d470https://doi.org/10.1161/circulationaha.111.049122
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