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groups, and a decrease in swelling degree values was observed in mediums with pH values of 5.5 and 7.4. The encapsulation and release efficiency of propolis decreased with an increase in the hydrogel cross-linking degree. UV irradiation enhanced the antioxidant activity of both free and encapsulated propolis. These findings offer valuable insights for the biomedical and pharmaceutical fields into designing biocompatible hydrogels for propolis immobilization, with potential for controlled release.
Mahmoudi et al. (2024) studied this question.