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August 1, 1978Thorax14 citationsOpen Access

Direct myocardial revascularisation: experience with 9364 operations.

DCDenton A. CooleyDWDon C. WukaschFBFrancesco Bruno

Key Result

Direct myocardial revascularisation using aortocoronary bypass in 9364 patients demonstrated a 3.9% early mortality rate for ACB alone, with an estimated 80% survival rate at 8 years.

Study Design

Type

Cohort (n=9,364)

Structured PICO

Does direct myocardial revascularisation using aortocoronary bypass improve survival and symptoms in patients with coronary insufficiency compared to medical treatment?

P
Population
9364 consecutive patients with coronary insufficiency
I
Intervention
Direct myocardial revascularisation using aortocoronary bypass (ACB)
C
Comparator
Medical treatment (based on comparison with other series of patients treated medically)
O
Outcome
Hospital (early) mortality and late survival (up to 8 years)hard clinical

Aortocoronary bypass surgery provides significant symptomatic relief and an estimated 80% 8-year survival in patients with coronary insufficiency, with early mortality decreasing over time.

Abstract

Between July 1968 and December 1976, 9364 consecutive patients with coronary insufficiency underwent direct myocardial revascularisation using aortocoronary bypass (ACB). Among these patients 8017 had ACB alone, and the remaining 1347 had ACB in addition to correction of other cardiac and vascular lesions. In the series of patients having ACB alone the hospital (early) mortality was 3.9%, but for 2383 surgical patients in 1976 this figure was 2.2%. Operative mortality was higher for women (6.85%) than for men (3.5%), but late survival was about the same for both sexes. Among surviving patients 88% were improved or symptom-free after undergoing ACB. According to our data, at the end of eight years 80% of the patients will be survivors. These results, when compared with other series of patients treated medically, indicate the superiority of surgical treatment both in terms of symptomatic relief and also in increased life expectancy.

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Cite This Study

Cooley et al. (1978) conducted a cohort in Coronary insufficiency (n=9,364). Direct myocardial revascularisation using aortocoronary bypass (ACB) vs. Medical treatment (historical comparison) was evaluated on Hospital (early) mortality for ACB alone. Direct myocardial revascularisation using aortocoronary bypass in 9364 patients demonstrated a 3.9% early mortality rate for ACB alone, with an estimated 80% survival rate at 8 years.

synapsesocial.com/papers/6a076a182edded7c7b8437cehttps://doi.org/10.1136/thx.33.4.411
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