Prospective cohort studies provide strong evidence that psychosocial factors, particularly depression and social support, are independent aetiological and prognostic factors for coronary heart disease.
Systematic Review
Do psychosocial factors influence the aetiology and prognosis of coronary heart disease in healthy populations and patients with CHD?
This systematic review highlights the significant role of psychosocial factors, especially depression and social support, in both the development and prognosis of coronary heart disease.
Summary points: In healthy populations, prospective cohort show a possible aetiological role for type /hostility (6/14 studies), depression and (11/11 studies), psychosocial work (6/10 studies), social support (5/8 studies). In populations of patients with coronary heart, prospective studies show a prognostic for depression and anxiety (6/6 studies), work characteristics (1/2 studies), social support (9/10 studies) ; none of five showed a prognostic role for type /hostility. this review can not discount the of publication bias, prospective cohort provide strong evidence that psychosocial, particularly depression and social support, independent aetiological and prognostic for coronary heart disease.
Hemingway et al. (1999) conducted a systematic review in coronary heart disease. Psychosocial factors (type A/hostility, depression and anxiety, work characteristics, social support) was evaluated on Fatal coronary heart disease, non-fatal myocardial infarction, or all-cause mortality. Prospective cohort studies provide strong evidence that psychosocial factors, particularly depression and social support, are independent aetiological and prognostic factors for coronary heart disease.