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November 10, 2007Journal of Bacteriology76 citationsOpen Access

LmrR Is a Transcriptional Repressor of Expression of the Multidrug ABC Transporter LmrCD in Lactococcus lactis

HAHerfita AgustiandariJLJacek LubelskiHSH. Bart van den Berg van Saparoea

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Abstract

LmrCD is an ABC-type multidrug transporter in Lactococcus lactis. LmrR encodes a putative transcriptional regulator. In a DeltalmrR strain, lmrCD is up-regulated. LmrR binds the promoter region of lmrCD and interacts with drugs that cause lmrCD up-regulation. This suggests that LmrR is a drug-dependent transcriptional regulator of lmrCD expression.

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Agustiandari et al. (2007) studied this question.

synapsesocial.com/papers/6a07dca75e9d1d45054abd1ehttps://doi.org/10.1128/jb.01151-07
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