Crystal Structureand Microstructural Growth of Gd(III)benzenetricarboxylic Metal Organic Framework (MOF) Under Facile Sonochemical Synthesis

Gadolinium is one of the rare earth elementswhich has high magnetic susceptibility due to its 7 unpaired 4f electrons(8 μB). This magnetic susceptibility can induce both T1and T2relaxation in tissue where Gd substance accumulated,therefore can affect the signal of Magnetic Resonance Imaging. Gadolinium-Based Contrast Agent (GBCA) is structurally based on a complex compound formed between Gd(III) ion and certain organic ligand such as carboxylic ligand. 1,3,5-benzenetricarboxylic acid (H3BTC) ligand is one of the multicarboxylate ligands that has the potential toform GBCA through complex-based Metal OrganicFramework (MOF). Gd-BTC complexes has been successfully synthesizedusing facile synthesis method of ultrasound wave irradiation at considerably facile time synthesisat 15, 30, and 45 minutes. The yield of white compound increaseswith anincreaseof synthesis time. The XRD powder analysis shows that the Gd-BTC complex is crystallized in a tetragonal crystal system with space group P4122. The degree of crystallinity of the obtained Gd-BTC complexes decreased as the synthesis time increased, while the crystal size increasedproportionallyto the synthesis time. SEM characterizationdisplaysthe microrod-like morphology with variousparticle sizes correspond to thetimeofsynthesis. Both thelength and thewidth of the particles obtained from each complex tend to decrease along with the prolongation of synthesis time.