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May 16, 2026Intelligent Systems with Applications0 citationsOpen Access

MMP: A hybrid AI approach for explainable diagnosis of concept drifts in patient pathways

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SASina Namaki AraghiFBFrédérick BénabenFFFranck Fontanili

Key Points

  • The aim is to develop a hybrid AI approach for diagnosing concept drifts in patient pathways using domain-specific knowledge.
  • Defined a meta-model to integrate domain knowledge into process mining.
  • Generated artificial traces to simulate process deviations.
  • Applied the ProDIST algorithm to assess and identify similar processes.
  • Successfully detected process drifts in healthcare applications with consistent accuracy.
  • Provided interpretable insights that helped identify potential causes of drifts.
  • Demonstrated the effectiveness of integrating domain knowledge in process mining analyses.

Abstract

Business processes in complex and dynamic environments, such as hospitals, are subject to constant changes. This could arise from adaptation to unforeseen events, creating uncertainty and inefficiency in clinical pathways. Traditionally grounded in sub-symbolic AI, Process Mining provides insights into process behavior through actions such as concept drift analysis, including detection , characterization , and explainability . However, most existing studies focus on drift detection, making it challenging to identify the root causes of process deviations. The literature indicates that this limitation largely stems from the difficulty of integrating domain-specific knowledge into process mining. This article targets this issue and presents the Minuscule Movement of business Processes (MMP) approach to diagnose drifts and deviations in patients’ pathways through two main steps. First, it defines a meta-model to embed domain knowledge such as potential causes of drifts into process discovery analyses and to generate artificial traces that simulate process deviations. In the second step, these traces are assessed using the proposed ProDIST algorithm to find the process most similar to the discovered workflow. The identified process is then used to diagnose and determine the root causes of the drift. MMP’s practical applicability is assessed through a real-life experiment in healthcare. Accordingly, MMP successfully detected process drifts in the healthcare case study, achieving consistent accuracy and providing interpretable insights that enabled domain experts to identify potential causes of process drifts and deviations. • Automated root-cause diagnosis of business processes within Process Mining, showcasing a comprehensive hybrid AI approach called MMP. • Demonstrating explainability in process mining. • A platform to integrate healthcare domain knowledge with the location data of patients. • Augmenting process mining analyses through embedding domain knowledge to explain causes of concept drifts. • Introducing the ProDIST algorithm to measure the distance between business processes.

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Cite This Study

Araghi et al. (2026) studied this question.

synapsesocial.com/papers/6a080969a487c87a6a40b5dehttps://doi.org/10.1016/j.iswa.2026.200669
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluating the utility of process analysis to understand the variations in the patient care pathways2026
  2. 2Analyzing Healthcare Processes with Incremental Process Discovery: Practical Insights from a Real-World Application2024 · 13 citations
  3. 3Optimizing Healthcare Business Processes with Process Mining Software: A Comparative Analysis2024 · 1 citations
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  5. 5Using Process Mining Techniques to Enhance the Patient Journey in an Oncology Clinic2026 · 1 citations