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May 16, 20260 citations

Ultrasound-based liver elastography: a narrative review of technical principles and interpretation of results.

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FSFernanda Fernandes SouzaRARoberta Chaves AraújoGFGuilherme Massotte Fontanin

Key Points

  • To summarize the technical principles and interpretation methods for ultrasound-based liver elastography in assessing liver fibrosis.
  • Narrative review of various ultrasound elastography techniques and their principles.
  • Discussion of factors influencing measurement reliability and clinically relevant cutoff values.
  • Evaluation of methodological limitations and factors that may confound results.
  • Ultrasound-based liver elastography demonstrated high accuracy and reliability for assessing liver fibrosis.
  • Technical quality and appropriate indications are critical for effective application in clinical settings.

Abstract

In recent years, noninvasive methods for assessing liver fibrosis have significantly transformed hepatology practices, reducing the need for liver biopsy. Among these, elastography techniques have become widely used tools for staging fibrosis in patients with chronic liver disease. Currently, various modalities are available, including transient elastography, point shear wave elastography, two-dimensional shear wave elastography, and magnetic resonance elastography; the first three are ultrasound-based techniques, whereas the last is a magnetic resonance imaging-based technique. In this context, ultrasound-based liver elastography stands out as a reliable, reproducible method with high accuracy. This narrative review aims to present the technical principles of ultrasound-based shear wave elastography, discuss the factors that influence measurement reliability, and provide practical guidance for result interpretation. The topics addressed include acquisition protocols, methodological limitations, potential confounding factors, and clinically relevant cutoff values. In conclusion, when applied under appropriate indications with adequate technical quality and interpretation, ultrasound-based liver elastography is a valuable, complementary tool for managing chronic liver disease.

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Cite This Study

Souza et al. (2026) studied this question.

synapsesocial.com/papers/6a080a71a487c87a6a40c6c7https://doi.org/10.1590/0100-3984.2025.0102
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