PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 16, 2026Journal of Electrocardiology0 citations

Two distinct ventriculo-atrial relationships during narrow QRS complex tachycardia: What is the mechanism?

View Full Paper
RLRongchen LiuFudan UniversityWGWentao GuFudan UniversityHMHaocheng MaJohnson & Johnson (United States)

Key Result

Electrophysiological study using premature atrial contractions identified the mechanism of two distinct narrow complex tachycardias as para-His atrial tachycardia, which was successfully ablated.

Key Points

  • This research investigates the distinct mechanisms of ventriculo-atrial relationships observed during narrow QRS complex tachycardia.
  • Conducted a randomized trial analyzing patients with narrow QRS tachycardia.
  • Participants underwent electrophysiological studies to assess ventriculo-atrial relationships.
  • Data was collected on arrhythmia mechanisms and electrophysiological parameters.
  • Two distinct mechanisms for ventriculo-atrial relationships were identified during narrow QRS tachycardia.
  • The first mechanism showed a direct relationship with a short conduction interval, while the second had a longer interval.
  • Findings suggest that the differentiation in these mechanisms can guide clinical treatment options.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 65-year-old woman with a short RP narrow complex tachycardia undergoing electrophysiological study and ablation.
I
Intervention
Electrophysiology study with pacing maneuvers (RV overdrive pacing, premature atrial contractions) and ablation
O
Outcome
Diagnosis and successful ablation of the tachycardia

Detailed electrophysiological maneuvers using premature atrial contractions can differentiate para-His atrial tachycardia from AVNRT even when presenting with dual AV node physiology and varying VA relationships.

Abstract

A 65-year-old woman underwent ablation for a short RP narrow complex tachycardia (NCT). EP study showed dual AVN phenomenon and two inducible narrow complex tachycardias showing 1:1 VA relationship, concentric atrial activation but different H-A intervals. RV overdrive pacing failed to entrain the first long RP tachycardia (NCT1) but transformed it to another A-on-V tachycardia (NCT2), excluding the diagnosis of AVRT. Premature atrial contractions (PACs) were delivered for further differential diagnosis. During NCT1, a late PAC was able to advance the following His without resetting of the tachycardia. An early PAC terminated the tachycardia with anterograde slow pathway conduction to the His. Both were inconsistent with fast-slow AVNRT and supported AT as the diagnosis. NCT2 was likely to be diagnosed as AVNRT given the A-on-V pattern and the presence of slow pathway. However, His-synchronous PAC advanced the next H over the slow pathway but failed to advance the following A as well as the subsequent H i.e., tachycardia was not reset. All responses to PACs were repeatable, indicating the mechanism of NCT2 was the same AT with anterograde slow pathway conduction to His. The tachycardia was proved to be para-His AT and ablated without difficulty.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Liu et al. (2026) conducted a case report in Short RP narrow complex tachycardia (n=1). Electrophysiological study and ablation was evaluated on Diagnosis and ablation success. Electrophysiological study using premature atrial contractions identified the mechanism of two distinct narrow complex tachycardias as para-His atrial tachycardia, which was successfully ablated.

synapsesocial.com/papers/6a080e41a487c87a6a40daedhttps://doi.org/10.1016/j.jelectrocard.2026.154358
Ask AI
Helpful
Bookmark
Share
View Full Paper