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November 21, 2025Neurology International1 citationsOpen Access

Post-Ablation Stroke Despite NOAC Use: Successful Reperfusion Therapy After Dabigatran Reversal with Incidental Discovery of a Large MCA Aneurysm—A Case Report

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SSS. SariWCWei‐Tso ChenCLChien-Hui Lee

Key Result

Idarucizumab reversal of dabigatran expands stroke reperfusion options by enabling both IVT and EVT in NOAC-treated patients.

Structured PICO

P
Population
1 patient with post-ablation stroke despite dabigatran use
I
Intervention
Idarucizumab reversal followed by intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT)
O
Outcome
Successful reperfusion

Idarucizumab reversal can safely enable both intravenous thrombolysis and endovascular thrombectomy in patients experiencing acute ischemic stroke while on dabigatran.

Abstract

This case illustrates how idarucizumab reversal expands reperfusion options by enabling both IVT and EVT in NOAC-treated patients and highlights the diagnostic role of EVT in revealing underlying vascular pathology, emphasizing the need for individualized post-procedural antithrombotic management.

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Cite This Study

Sari et al. (2025) studied this question. Idarucizumab reversal of dabigatran expands stroke reperfusion options by enabling both IVT and EVT in NOAC-treated patients.

synapsesocial.com/papers/6a085f843d5e33e4691083cdhttps://doi.org/10.3390/neurolint17120190
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