Key points are not available for this paper at this time.
This report describes the use of a planar-chiral bipyridine ligand to achieve the first diastereo- and enantioselective copper-catalyzed 4+1 cycloadditions of enones with diazo compounds to produce highly substituted 2,3-dihydrofurans. The method is applied to a catalytic asymmetric synthesis of a deoxy-C-nucleoside.
Son et al. (2007) studied this question.