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March 1, 1972Annual Review of Physiology62 citations

Regulation of Cardiac Contraction

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JRJ RossBSBurton E. Sobel

Key Result

This review summarizes recent advances in biochemical integration, structure-function relations, ventricular function assessment, and factors affecting mammalian heart performance.

Key Points

  • This review focuses on recent advancements in cardiac contraction regulation and factors influencing heart performance.
  • Review of literature on biochemical integration in myocardial cells and factors affecting cardiac function.
  • Analysis of structure-function relationships in contractile units of muscle and heart.
  • Assessment methods for ventricular function and integrated neural control mechanisms.
  • Identified significant advancements in understanding biochemical processes in myocardial cells.
  • Highlighted the importance of structure-function relations in cardiac muscle contraction.
  • Reviewed various methods for assessing ventricular function and their implications for cardiac health.

PICO

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Population
Cardiac contraction

Abstract

Primary emphasis in this review will be placed o n recent significant ad­ vances in the following four areas: Biochemical integration in the myocardial cell (page 47). Structure-function relations in the contractile units of muscle and heart (page 156) . Methods for the assessment of ventricular function (page 161). Factors which affect the performance of the mammalian heart (page 71) . Important topics largely omitted which have received comprehensive review elsewhere include Mommaerts' review of the energetics of muscular contraction (1), Young's analysis of the molecular basis of muscular con­ traction (2), the review by Katz on contractile proteins of the heart (3) , Korner's review of integrated neural control mechanisms (4) , Johnson & Lieberman's analysis of excita tion-contraction coupling and the structure of the sarcotubular system (5) , and Levy & Berne's review of cardiac neural control and the coronary circulation (6).

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Ross et al. (1972) conducted a review in Cardiac contraction. This review summarizes recent advances in biochemical integration, structure-function relations, ventricular function assessment, and factors affecting mammalian heart performance.

synapsesocial.com/papers/6a0909c314243797f79d0efbhttps://doi.org/10.1146/annurev.ph.34.030172.000403
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