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February 25, 2025Scientific Reports4 citationsOpen Access

Acute effects of high-intensity interval training and moderate-intensity continuous training on executive functions in healthy older adults

SAShirko AhmadiMBMathieu BélangerMOMyles W. O’Brien

Key Result

High-intensity interval training yielded a significantly greater reduction in Switching reaction time by 73.6 ms compared to moderate-intensity continuous training 45 minutes post-exercise.

Study Design

Type

RCT (n=25)

Randomization

Randomized counterbalanced order

Multicenter

No

Structured PICO

Does high-intensity interval training improve executive functions compared to moderate-intensity continuous training in healthy older adults?

P
Population
25 healthy community-dwelling older adults (10 males, 15 females), average age 67.1 ± 4.5 years, cognitively healthy (MMSE ≥ 25), recreationally active.
I
Intervention
High-intensity interval training (HIIT) on a cycle ergometer (15s at 100% peak power output, 15s rest, 2 × 20 min with 5 min rest between sets)
C
Comparator
Moderate-intensity continuous training (MICT) on a cycle ergometer (34 min at 60% peak power output)
O
Outcome
Reaction times for Naming, Inhibition, and Switching conditions of a computerized modified Stroop Task, measured immediately after and 45 min post-trainingsurrogate

A single session of high-intensity interval training provides a greater and more sustained improvement in cognitive flexibility (switching tasks) compared to moderate-intensity continuous training in healthy older adults.

Main Result

Effect estimate: Mean difference 73.6 ms

Absolute Event Rate: -147.1% vs -91.5%

p-value: p=0.019

Limitations

  • Conducted on cognitively healthy adults, so the applicability of the findings to those with cognitive impairments is uncertain
  • Energy expenditure during the rest intervals of the HIIT protocol was not measured
  • Baseline measurements were not performed just prior to exercise
  • Conducted on cognitively healthy adults, so applicability to those with cognitive impairments is uncertain
  • Study design does not allow to establish mechanistic underpinnings

Abstract

Numerous studies have demonstrated that executive functions benefit from high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT). However, the immediate effects of HIIT and MICT on these functions in older adults have not been compared. This study aimed to examine the acute impact of HIIT and MICT on executive function components in this demographic. Twenty-five healthy community-dwelling older adults (15 females; average age 67.1 ± 4.5 years) participated. The study involved three sessions: an initial session with cognitive assessments (Stroop Task: Naming, Inhibition, and Switching) and a maximal continuous graded exercise test, followed by two sessions involving HIIT (15s at 100% peak power output, 15s rest, 2 × 20 min) or MICT (34 min at 60% peak power output) training protocols in random order. Cognitive tests were administered immediately after and 45 min post-training. The results showed a significant difference in Switching reaction times between MICT and HIIT, with HIIT showing a greater reduction in Switching times after 45 min (p = 0.019). In conclusion, our study indicates that HIIT's beneficial effects on executive functions demonstrated a larger effect size than those of MICT. This suggests that brief, high-intensity exercise could be more effective in enhancing executive functions among older adults.

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Cite This Study

Ahmadi et al. (2025) conducted an RCT in Healthy older adults (n=25). High-intensity interval training (HIIT) vs. Moderate-intensity continuous training (MICT) was evaluated on Switching reaction time 45 minutes post-exercise (Mean difference 73.6 ms, p=0.019). High-intensity interval training yielded a significantly greater reduction in Switching reaction time by 73.6 ms compared to moderate-intensity continuous training 45 minutes post-exercise.

synapsesocial.com/papers/6a09e72d30285ee4a134219ehttps://doi.org/10.1038/s41598-025-91833-z
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