Focal takotsubo cardiomyopathy accounted for 6.9% of cases and was associated with a higher left ventricular ejection fraction (56%) compared to apical (45%) and mid-ventricular (46%) types (P=0.03).
Observational (n=144)
What is the prevalence and what are the clinical features of focal takotsubo cardiomyopathy compared to other types of takotsubo cardiomyopathy?
Focal takotsubo cardiomyopathy accounts for approximately 6.9% of takotsubo cases and presents with a higher left ventricular ejection fraction compared to apical and mid-ventricular variants, though in-hospital outcomes are similar.
p-value: p=0.03
BACKGROUND: Because it is difficult to distinguish between focal takotsubo cardiomyopathy and aborted myocardial infarction, there is little information about the prevalence and clinical features of focal takotsubo cardiomyopathy. METHODS AND RESULTS: Our cardiac catheterization databases were queried to identify patients with focal takotsubo cardiomyopathy and other types of takotsubo cardiomyopathy. We defined focal takotsubo cardiomyopathy as hypo-, a- or dyskinesis in both anterolateral and septal segments without obstructive coronary artery disease explaining the wall motion abnormality. A total of 10 patients were diagnosed with focal takotsubo cardiomyopathy. The control group comprised patients with takotsubo cardiomyopathy with apical, mid-ventricular, or basal ballooning. Clinical features and in-hospital outcomes were compared between patients with focal takotsubo cardiomyopathy and those with other types of takotsubo cardiomyopathy. Among the 144 patients with takotsubo cardiomyopathy, the apical, mid-ventricular, basal, and focal types occurred in 85 (59.0%), 49 (34.0%), 0 (0%), and 10 patients (6.9%), respectively. The left ventricular ejection fraction was significantly higher in the focal group compared with the apical and mid-ventricular group (56±13 vs. 45±13 vs. 46±12%, P=0.03). In-hospital outcome was not significantly different among the 3 groups. CONCLUSIONS: Focal takotsubo cardiomyopathy is not rare. Biplane left ventriculography is useful for its diagnosis. (Circ J 2016; 80: 1824-1829).
Kato et al. (2016) conducted an observational in Takotsubo cardiomyopathy (n=144). Focal takotsubo cardiomyopathy vs. Apical, mid-ventricular, or basal takotsubo cardiomyopathy was evaluated on Left ventricular ejection fraction (p=0.03). Focal takotsubo cardiomyopathy accounted for 6.9% of cases and was associated with a higher left ventricular ejection fraction (56%) compared to apical (45%) and mid-ventricular (46%) types (P=0.03).