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May 18, 2026Annals of Emergency Medicine0 citationsOpen Access

SGLT-2 Use and Hypoglycemic Ketoacidosis

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BJBenjamin A. JohnsonJohns Hopkins UniversityAAAreeba A. AbidStanford UniversityLSLuz SilverioKaiser Permanente Santa Clara Medical Center

Key Points

  • The report aims to outline a unique case of hypoglycemic nondiabetic ketoacidosis and the related treatment challenges.
  • Detailed case report of a patient with severe hypoglycemic nondiabetic ketoacidosis.
  • Assessment of symptoms and treatment approach in the emergency department.
  • Patient presented with severe hypoglycemic nondiabetic ketoacidosis requiring insulin intervention.
  • Diagnostic uncertainty was highlighted due to atypical presentation.

Abstract

Diabetic ketoacidosis is a life-threatening endocrine disorder frequently treated by emergency physicians. However, ketoacidosis variations, such as euglycemic diabetic ketoacidosis and nondiabetic ketoacidosis, can produce diagnostic uncertainty and delay initiation of appropriate treatment. This case report examines a patient with an unusual presentation of severe hypoglycemic, nondiabetic ketoacidosis requiring insulin.

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Cite This Study

Johnson et al. (2026) studied this question.

synapsesocial.com/papers/6a0aabf55ba8ef6d83b6f992https://doi.org/10.1016/j.annemergmed.2026.04.009
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