The Circulatory Risk in Communities Study (CIRCS) is a long-term dynamic prospective cohort study of over 65,000 Japanese adults that has identified key risk factors and prevention strategies for cardiovascular disease over 55 years.
Cohort (n=65,000)
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The Circulatory Risk in Communities Study (CIRCS) is a major, long-term prospective cohort study that has contributed to identifying CVD risk factors and developing prevention strategies in Japan over the past 50 years.
The Circulatory Risk in Communities Study (CIRCS) is an ongoing community-based epidemiological study of lifestyle-related disease involving dynamic prospective cohorts of approximately 12,000 adults from five communities of Japan: Ikawa, Ishizawa and Kita-Utetsu (Akita Prefecture), Minami-Takayasu (Osaka Prefecture), Noichi (Kochi Prefecture), and Kyowa (Ibaraki Prefecture). One of the most notable features of CIRCS is that it is not only an observational cohort study to identify risk factors for cardiovascular diseases (CVD), such as stroke, coronary heart disease, and sudden cardiac death, but it also involves prevention programs for CVD. Using basic, clinical, epidemiological, and statistical techniques, CIRCS has clarified characteristics of CVD and the related risk factors to develop specific methodologies towards CVD prevention in Japanese middle-aged or older adults for more than half a century.
Yamagishi et al. (2018) conducted a cohort in Cardiovascular disease (n=65,000). Observational cohort was evaluated on Incidence of stroke, coronary heart disease, and sudden cardiac death. The Circulatory Risk in Communities Study (CIRCS) is a long-term dynamic prospective cohort study of over 65,000 Japanese adults that has identified key risk factors and prevention strategies for cardiovascular disease over 55 years.