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March 31, 2005International Journal of Epidemiology7 citations

Pre-hospital coronary care and coronary fatality in the Belfast and Glasgow MONICA populations

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WMWayne E. MooreFKFrank KeeAEA. E. Evans

Key Result

Pre-hospital care in Belfast was associated with a lower 28-day case fatality following an acute coronary event (40.2%) compared to Glasgow (46.7%), likely due to shorter delays to specialist care.

Study Design

Type

Observational

Multicenter

Yes

Structured PICO

Does the model of pre-hospital care provision affect coronary event case fatality in populations with acute coronary events?

P
Population
Populations in Belfast and Glasgow with acute coronary events from the MONICA registers (1988, 1989, 1990, 1992, 1993)
I
Intervention
Belfast model of pre-hospital care provision (including mobile coronary care unit responses and earlier intervention)
C
Comparator
Glasgow model of pre-hospital care provision
O
Outcome
Coronary event case fatality at 28 dayshard clinical

Shorter delays between coronary event onset and access to specialist coronary care are associated with lower 28-day and pre-hospital case fatality.

Main Result

Absolute Event Rate: 40.2% vs 46.7%

Abstract

BACKGROUND: The aim of this study was to describe and compare coronary event case fatality and care pathways in two defined populations with access to different models of pre-hospital care provision. METHODS: Secondary analysis of MONItoring of Trends and Determinants in CArdiovascular Disease (MONICA) population coronary event registers (1988, 1989, 1990, 1992 and 1993). RESULTS: Case fatality at 28 days following an acute coronary event was 6.5% greater in the Glasgow MONICA Project (GMP) population (46.7%) than in the Belfast MONICA Project (BMP) population (40.2%). Pre-hospital case fatality was 33.9% in the GMP population and 28.3% in the BMP population. These differences could not be fully explained by mobile coronary care unit (MCCU) responses in the BMP area. Initial care was provided in hospital for 28.3% of the BMP events and only 7.7% of the GMP events. Additional data collected by the Belfast and Glasgow MONICA investigators support a large difference between the median delay to main medical care in the BMP events (120 min) and the median delay to ward admission in the GMP area (220 min) at this time. CONCLUSIONS: Our findings suggest that the delay between coronary event onset and access to specialist coronary care was the most likely critical difference, irrespective of hospital-based MCCU provision in the BMP area. An established 'culture of early intervention' in Belfast may have been an important factor. As a large proportion of coronary event fatalities continue to occur outside hospital, there is a need to strengthen the evidence base underpinning the provision of appropriate skilled care and treatment at the earliest possible opportunity.

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Cite This Study

Moore et al. (2005) conducted an observational in Acute coronary event. Pre-hospital care provision in Belfast vs. Pre-hospital care provision in Glasgow was evaluated on Case fatality at 28 days following an acute coronary event. Pre-hospital care in Belfast was associated with a lower 28-day case fatality following an acute coronary event (40.2%) compared to Glasgow (46.7%), likely due to shorter delays to specialist care.

synapsesocial.com/papers/6a0b3d7be1320844825d2bf4https://doi.org/10.1093/ije/dyh377
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