A 90-minute bout of weightlifting caused a transient decrease in diastolic filling (E:A ratio 1.78 vs 1.33, p<0.05) without altering LV contractility or causing myocyte damage.
Observational (n=17)
Does a 90-min bout of weightlifting exercise alter left ventricular function or cause cardiomyocyte damage in young male subjects?
Prolonged weightlifting causes a transient reduction in diastolic filling and stroke volume without impairing LV contractility or causing cardiomyocyte damage.
The purpose of this study was to assess left ventricular (LV) function and biochemical markers of myocyte after prolonged weightlifting activity. Seventeen male subjects (age range 20-34 years) performed a 90-min bout of weightlifting exercise consisting of three sets of 8-10 repetitions at 70% one-repetition maximum. Body mass, heart rate, systolic blood pressure (SBP) and echocardiographically determined indices of LV loading (LV internal diameter during diastole, LV meridonial wall stress), systolic function (stroke volume (SV), ejection fraction (EF), end-systolic pressure volume relationship; SBP/ESV) and diastolic filling (ratio of early to late; E:A) were obtained pre-exercise, immediately after and 24 h post-exercise. A 5-ml venous blood sample was obtained for the assessment of cardiac troponin T (cTnT) via third generation electrochemiluminescence assay. Data were assessed via one-way ANOVA and Pearson's correlation. Although SV declined (80.9 +/- 18.3 vs. 66.9 +/- 17.2, p 0.05). The E:A ratio was significantly decreased following exercise (1.78 +/- 0.41 vs. 1.33 +/- 0.37, p < 0.05). This decrease was not fully explained by loading conditions (r2 = 0.05 to 0.24). All values returned to baseline 24 h post-exercise. No cTnT was reported in any of the blood samples. In conclusion, there was no significant evidence of any LV contractile depression and no cTnT was observed post exercise. The small reduction in diastolic filling could not be explained by changes in haemodynamic loading or the post-exercise elevation in heart rate.
Stephenson et al. (2005) reported an observational. Weightlifting exercise vs. Pre-exercise baseline was evaluated on Left ventricular function and cardiac troponin T. A 90-minute bout of weightlifting caused a transient decrease in diastolic filling (E:A ratio 1.78 vs 1.33, p<0.05) without altering LV contractility or causing myocyte damage.