Tumoral calcinosis is an uncommon ectopic calcification disorder that typically affects the periarticular soft tissue but rarely involves the cervical muscles. We report a 40-year-old male with an end-stage renal disease secondary to IgA nephropathy, who presented with a slowly enlarging right neck mass with tenderness and partial limitation of neck movement. Ultrasonography and contrast-enhanced CT demonstrated a multilobulated, densely calcified mass like lesion arising from the cervical muscles, displacing major neck vessels anteriorly. Serum studies revealed hyperphosphatemia with secondary hyperparathyroidism, which was diagnosed as secondary tumoral calcinosis. The mass was completely excised without complication. Histopathology showed amorphous calcified deposits surrounded by foreign-body giant cells. During 22 months of clinical and imaging follow-up, no recurrence has been observed. This case underscores the need to include tumoral calcinosis in the differential diagnosis of calcified cervical masses in dialysis patients in order that phosphate control and definitive surgery may achieve favorable outcomes.
Lee et al. (2026) studied this question.