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May 12, 2004Journal of Virology874 citationsOpen Access

Memory CD8 T-Cell Differentiation during Viral Infection

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EWE. John WherryRARafi Ahmed

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Abstract

Memory CD8 T cells are an important component of protective immunity against viral infections, and understanding their development will aid in the design of optimal vaccines. Recent work has shed light on the complex differentiation process that occurs during a CD8 T-cell response to viral infection

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Wherry et al. (2004) studied this question.

synapsesocial.com/papers/6a0cdc3bedb32e8d90026238https://doi.org/10.1128/jvi.78.11.5535-5545.2004
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Also Consider

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  1. 1Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment2003 · 1,618 citations
  2. 2T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions1998 · 2,630 citations
  3. 3Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice1994 · 324 citations
  4. 4CD7 Is a Differentiation Marker That Identifies Multiple CD8 T Cell Effector Subsets2003 · 91 citations
  5. 5Role of CD28-B7 Interactions in Generation and Maintenance of CD8 T Cell Memory2001 · 192 citations