Population
Biophysically based computer model of human atria
Design
Preclinical
Key result
A biophysically based computer model confirmed that cardiac wavelength must be below a critical value for atrial fibrillation to be sustained via multiple re-entrant wavelets.
Authors
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Requires wavelet dynamics knowledge for AF wavelength interpretation; leaves open clinical translation to human reentry management.
Computer modeling demonstrates that accurate interpretation of cardiac wavelength in atrial fibrillation requires prior knowledge of the underlying wavelet dynamics.
Jacquemet et al. (2005) studied Atrial fibrillation. Computer model of human atria was evaluated on Relationship between wavelength and AF perpetuation. A biophysically based computer model confirmed that cardiac wavelength must be below a critical value for atrial fibrillation to be sustained via multiple re-entrant wavelets.