A baseline left atrial sphericity index >0.9 independently predicted atrial fibrillation recurrence after successful direct-current cardioversion (OR 4.1 to 7.6).
Cohort (n=124)
Does a baseline left atrial sphericity index (LASI) >0.9 predict atrial fibrillation recurrence in patients with persistent AF after successful direct-current cardioversion?
A baseline left atrial sphericity index >0.9 measured by 2D echocardiography strongly predicts atrial fibrillation recurrence within 12 months after successful direct-current cardioversion.
Effect estimate: OR 4.1 to 7.6 (95% CI 1.6-11.9 to 3.3-19.7)
p-value: p=0.005 to 7.2 x 10(-6)
BACKGROUND: Attempts to achieve rhythm control using direct-current cardioversion (DCC) are common in those with persistent atrial fibrillation (AF). Although often successful, AF recurs within 1 month in as many as 57% of patients. The aim of this study was to assess whether a baseline left atrial sphericity index (LASI) acquired by 2-dimensional transthoracic echocardiography (TTE) could be used as a predictor of AF recurrence after successful DCC. HYPOTHESIS: A baselline LASI assessed by 2D TTE can predict AF recurrence after successful DCC in patients with persistent AF. METHODS: A total of 124 consecutive patients with persistent AF lasting 0.9) proved to be a strong and independent predictor of AF recurrence, with an odds ratio between 4.1 (95% confidence interval: 1.6-11.9, P = 0.005) and 7.6 (95% confidence interval: 3.3-19.7; P = 7.2 × 10(-6) ). The receiver operating characteristic curve indicated good power for distinguishing between recurring and nonrecurring AF, and we chose a cutoff of 0.9 because high specificity was a priority for clinical reasons. CONCLUSIONS: In conclusion, baseline LASI >0.9 was associated with significantly greater AF recurrence throughout the 12-month follow-up period.
Osmanagic et al. (2016) conducted a cohort in Persistent atrial fibrillation (n=124). Baseline left atrial sphericity index (LASI) >0.9 vs. LASI ≤0.9 was evaluated on Atrial fibrillation recurrence after successful direct-current cardioversion (OR 4.1 to 7.6, 95% CI 1.6-11.9 to 3.3-19.7, p=0.005 to 7.2 x 10(-6)). A baseline left atrial sphericity index >0.9 independently predicted atrial fibrillation recurrence after successful direct-current cardioversion (OR 4.1 to 7.6).