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June 1, 2003Asian Cardiovascular and Thoracic Annals28 citations

The Prevalence and Clinical Profile of Angiographic Coronary Ectasia

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PNPeter NyamuMAMullasari S. AjitPJPeter K. Joseph

Key Result

Isolated coronary ectasia was identified in 2% of 6938 angiograms, with 25% of symptomatic patients presenting with or having a history of myocardial infarction.

Study Design

Type

Observational (n=6,938)

Multicenter

No

Structured PICO

P
Population
6,938 patients who underwent coronary angiogram over a six-year period at a single institute, focusing on a subset of 134 patients (2%) with isolated coronary ectasia.
O
Outcome
Prevalence, clinical presentation, and angiographic characteristics of isolated coronary ectasia.

Isolated coronary ectasia has a 2% angiographic prevalence and is associated with a significant rate of myocardial infarction, indicating it is not a benign condition.

Abstract

Coronary artery ectasia, a variant of coronary atherosclerosis, is a relatively rare entity. Review of literature did not reveal an exclusive study on isolated ectasia. We decided to analyse the clinical presentation and angiographic prevalence of this subset. A retrospective study of patients who underwent coronary angiogram in our institute over the past six years was carried out and the epidemiological, clinical and angiographic characteristics of patients with isolated ectasia were analysed. Distribution of ectasia was with a modification of the Markis classification. Among 6938 angiograms analysed, 134 (2%) had isolated ectasia. Of the 118 symptomatic patients, 34 (25%) had a history of or presented with infarction, with correlation between the territory of infarction and the ectatic vessel in 32 patients. Of 62 patients with lipid abnormality, Hypertriglyceridemia in 42 (65%) was the most common. The left anterior descending artery was the most common vessel involved. Diffuse ectasia most commonly involved the right coronary artery. One patient had spontaneous coronary dissection. There is a relatively high prevalence of isolated coronary ectasia with predominant involvement of the right coronary vessel when diffuse and the left anterior descending artery when discrete. This entity is not innocuous and warrants a detailed study on the available management options.

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Cite This Study

Nyamu et al. (2003) conducted an observational in Isolated coronary ectasia (n=6,938). Isolated coronary ectasia was identified in 2% of 6938 angiograms, with 25% of symptomatic patients presenting with or having a history of myocardial infarction.

synapsesocial.com/papers/6a0d3db336162e2f4b09a891https://doi.org/10.1177/021849230301100207
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