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May 20, 2026Sensors0 citationsOpen Access

An Automated Fluorescence Microscopy-Based Sensing System for Continuous Detection of Airborne Asbestos Fibers on a PM2.5 Monitoring Platform

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AKAkio KurodaKKKenichiro KagaTNTomoki Nishimura

Key Points

  • The study aims to design and develop an automated system for continuous detection of airborne asbestos fibers using fluorescence microscopy.
  • Developed an automated FM-based sensing system integrated with a commercial PM2.5 monitoring platform.
  • Implemented automated fluorescent staining and AI-assisted image analysis for fiber detection.
  • Evaluated system performance against conventional PCM and scanning electron microscopy measurements.
  • The automated system showed overall agreement within 14.1% compared to PCM-scanning electron microscopy measurements.
  • Notable variability occurred at low fiber concentrations due to stochastic sampling effects.
  • Results confirm the system's feasibility for environmental monitoring of airborne asbestos fibers.

Abstract

Despite regulations restricting asbestos use in many developed countries, asbestos-containing materials (ACMs) persist in aging buildings and can release airborne fibers during demolition and renovation. Therefore, continuous monitoring of airborne asbestos fibers is essential for environmental safety and exposure assessment. Fluorescence microscopy (FM) with fluorescently labeled asbestos-binding proteins offers greater sensitivity and selectivity in detection compared with conventional phase contrast microscopy (PCM). However, its practical application is limited by manual sample preparation and microscopic observations. This study introduces the conceptual design and initial development of an automated FM-based sensing system for monitoring airborne asbestos fibers. The system was constructed by modifying a commercial PM2.5 continuous air sampling platform and integrating automated fluorescent staining, FM imaging, and AI-assisted image analysis for fiber recognition and counting. The system automatically reports airborne asbestos concentrations with corresponding fluorescence images and advances the membrane filter to enable continuous measurements. Performance evaluation using pulverized ACMs showed an overall agreement within 14.1% with PCM–scanning electron microscopy measurements at the group level. Although variability was observed at low fiber concentrations owing to stochastic sampling effects, the results validate the feasibility of automated FM-based sensing for continuous environmental monitoring of airborne asbestos fibers.

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Cite This Study

Kuroda et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5089f03e14405aa9c53ahttps://doi.org/10.3390/s26103163
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