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May 20, 20260 citationsOpen Access

The Importance of Optical Coherence Tomography in Diagnosing Optic Nerve Damage in Vertebrobasilar Insufficiency

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NXN.N. XasanovAlfred University

Key Points

  • The study aims to assess optic nerve damage through RNFL thickness measurements in patients with central vertigo and vertebrobasilar insufficiency.
  • Utilized optical coherence tomography (OCT) to measure retinal nerve fiber layer (RNFL) thickness.
  • Compared RNFL thickness in patients with early-stage central vertigo with and without vertebrobasilar stenosis.
  • Emphasized careful medical history assessment to understand symptom onset.
  • Patients with vertebrobasilar stenosis showed a significant reduction in RNFL thickness compared to those without stenosis.
  • Statistical analysis indicated a p-value of <0.05 for RNFL differences between groups.

Abstract

The diagnosis of vertebrobasilar arterial insufficiency is based on a characteristic symptom complex that encompasses several groups of clinical symptoms observed in patients with AS and hypertension. These include visual and oculomotor disturbances, impaired statics and motor coordination, and vestibular disturbances. A presumptive diagnosis is based on at least two of these symptoms. These symptoms are short-lived and often resolve spontaneously, although they are signs of impaired blood flow in the arteries of this system, requiring clinical and instrumental examination. A thorough medical history is especially necessary to clarify the circumstances of the onset of these symptoms. The aim of this study was to evaluate differences in mean retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) in patients with early-stage central vertigo, with or without vertebrobasilar stenosis, detected by Doppler ultrasonography.

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Cite This Study

N.N. Xasanov (2026) studied this question.

synapsesocial.com/papers/6a0d5098f03e14405aa9c813https://doi.org/10.5281/zenodo.20271700
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Optical Coherence Tomography and Optical Coherence Tomography Angiography in Optic Nerve Disorders2024
  2. 2Can Optical Coherence Tomography Angiography be a Useful Adjunctive Diagnostic Tool in Patient with Non Arteritic Ischaemic Optic Neuropathy?2024
  3. 3Characterization of Peripapillary Vascular Density in Traumatic Optic Neuropathy2026
  4. 4Diagnostic Accuracy of Optical Coherence Tomography in Patients with Optic Neuritis2025
  5. 5Correlation of Retinal Nerve Fibre Layer Thickness in Optical Coherence Tomography with Visual Outcome in Optic Neuritis2024