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May 20, 2026American Journal of Respiratory and Critical Care Medicine

A42-14 Fentanyl Is the Silent Killer

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Authors

HBH BdairLAL AbdelghaniCTC Tashdjian

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Overview

Case report reveals muscle rigidity and respiratory distress in a patient after fentanyl use, indicating need for awareness.

Key Points

  • This case report aims to highlight the rare complication of Wooden Chest Syndrome (WCS) associated with high-dose fentanyl therapy.
  • Describing a case of a 48-year-old female with respiratory distress and muscle rigidity due to fentanyl.
  • Patient underwent bronchoscopy after intubation and was treated with various respiratory therapies.
  • Fentanyl infusion was stopped after worsening respiratory parameters were observed.
  • Patient's plateau pressures improved within 12-24 hours after discontinuation of fentanyl.
  • The patient was extubated successfully after significant respiratory improvement.
  • Demonstrated severe muscle rigidity and respiratory failure linked to extended fentanyl infusion.

Cite This Study

Bdair et al. (2026) studied this question.

synapsesocial.com/papers/6a0d50aff03e14405aa9cb0ehttps://doi.org/10.1093/ajrccm/aamag162.2950
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