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May 20, 2026American Journal of Respiratory and Critical Care Medicine

B72-42 An Unusual Case of Endobronchial Aspergilloma in a Young Immunocompetent Adult Presenting as Refractory Asthma

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Authors

ZHZ HussainSGS GillMSM Shafqat

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Overview

Case presentation reveals diagnostic challenges of endobronchial aspergilloma in a young adult, suggesting the need for careful evaluation.

Key Points

  • To highlight an unusual case of endobronchial aspergilloma in a young immunocompetent male misdiagnosed as refractory asthma.
  • Reviewed clinical history of a 25-year-old male with recurrent respiratory symptoms and negative initial evaluations.
  • Conducted high-resolution CT scans and flexible bronchoscopy to assess pulmonary abnormalities.
  • Administered oral voriconazole following identification of Aspergillus species through histopathology.
  • Flexible bronchoscopy identified a white endobronchial lesion with fungal hyphae consistent with Aspergillus species.
  • Initiation of voriconazole treatment led to complete clinical, bronchoscopic, and radiological resolution of symptoms.
  • Case highlights the rarity and diagnostic complexity of EBA in immunocompetent individuals.

Cite This Study

Hussain et al. (2026) studied this question.

synapsesocial.com/papers/6a0d50f3f03e14405aa9d2b0https://doi.org/10.1093/ajrccm/aamag162.4331
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endobronchial Aspergillosis Presenting as an Isolated Airway Lesion in an Immunocompromised Patient2026
  2. 2Coexistence of endobronchial aspergilloma, pulmonary embolism, and lung cancer: a case report2025
  3. 3Tracheobronchial Aspergillosis Mimicking Pseudotumoral Lesions in a Rare Presentation of a Known Disease2025
  4. 4C32-06 Allergic Bronchopulmonary Aspergillosis in a Non-Asthmatic Individual: An Uncommon Presentation2026
  5. 5B72-44 Recurrent Allergic Bronchopulmonary Aspergillosis Presenting as Persistent Right Middle Lobe Opacity in an Immunocompetent Patient2026